Yahoo Mail adds simple Flickr photo sharing

Many criticized a pre-Marissa Mayer Yahoo for doing little to integrate acquisitions with its core services, even when they were popular services like Del.icio.us. We can't accuse the company of negligence today, as it just added simple Flickr photo sharing to Yahoo Mail. Those drafting messages just have to tap an arrow to attach files from their photo streams, and they can sign up for Flickr on the spot. While there's only so many of us who could use Flickr sharing right now, Yahoo teases that there are more Mail upgrades in the pipeline -- it's not done fighting Gmail and Outlook just yet.

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Source: Yahoo (Tumblr)

Source: http://www.engadget.com/2013/06/28/yahoo-mail-adds-simple-flickr-photo-sharing/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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ASTRO Chairman Michael Steinberg, M.D., FASTRO, reaffirms Society's commitment to ending self-referral

Public release date: 27-Jun-2013
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Contact: Michelle Kirkwood
press@astro.org
703-286-1600
American Society for Radiation Oncology

JAMA study reveals 12 to 21 percent increase in advanced radiation treatment for low-risk prostate cancer patients

Fairfax, Va., June 27, 2013 A new study, "Use of Advanced Treatment Technologies Among Men at Low Risk of Dying from Prostate Cancer," published Tuesday, June 25, 2013, in the Journal of the American Medical Association (JAMA), by Bruce L. Jacobs, MD, MPH, et. al., analyzes treatment data for 55,947 prostate cancer patients (aged 66 years or older) in the Surveillance, Epidemiology and End Results (SEER)-Medicare database from 2004 to 2009. The study found that the use of advanced treatment technologies increased from 32 percent to 44 percent among men with low-risk prostate cancer, from 36 percent to 57 percent among men with high risk of non-cancer mortality, and from 13 percent to 24 percent among men unlikely to die from prostate cancer. In discussion, Dr. Jacobs, et. al., raise several concerns about increased treatment: "aggressive direct-to-consumer marketing and incentives associated with fee-for-service payment may promote the use of advanced treatment technologies;" "more diligence is needed to reduce the potentially unnecessary treatment of men with a low risk of dying from prostate cancer;" and "more immediately, policy change may help curtail the excessive use of advanced treatment technologies among patients least likely to benefit."

Michael L. Steinberg, MD, FASTRO, chairman of the American Society for Radiation Oncology's (ASTRO) Board of Directors, states that Dr. Jacobs, et.al.'s study reaffirms the Society's commitment to closing the self-referral loophole for radiation therapy within the Ethics in Patient Referrals Act, also known as the self-referral law.

ASTRO supports the use of intensity modulated radiation therapy (IMRT) as an appropriate, effective treatment for prostate cancer patients, however, IMRT should be carefully considered along with other effective treatments and management options, including active surveillance, by patients and their doctors. Treatment decisions should not be based on the physician's potential for profit, yet we believe profit-motivated IMRT overuse is rampant due to the proliferation of urology ownership of radiation therapy centers. The abuse of this expensive technology is allowed by a loophole in the federal physician self-referral law. We agree with Dr. Jacobs et. al.'s concerns that financial incentives may be negatively impacting treatment decisions, which we believe are compounded by ownership arrangements protected under the self-referral loophole.

ASTRO expects several independent studies will be published soon demonstrating that self-referral abuse in prostate cancer treatment, particularly among older men, is leading to unnecessary treatment, higher spending and inappropriate patient care. These new reports will add to the already significant body of evidence condemning self-referral abuse. In September 2012, a New England Journal of Medicine article authored by leading health policy experts called for closing the self-referral loophole for radiation therapy and other so-called "ancillary services." In the same month, the GAO issued a scathing report on self-referral in advanced diagnostic imaging titled "Higher Use of Advance Imaging Services by Providers Who Self-Refer Costing Medicare Millions" (GAO-12-966). On November 6, 2012, Bloomberg News published an investigative report indicting self-referral by demonstrating the real-world impact on patients' lives, which received in-depth follow-up by the local newspaper, the Monterey County Herald.

Cumulatively, all of these studies demonstrate that self-referral abuse drives overutilization of expensive technologies. Recently, several bipartisan groups, including the Bipartisan Policy Center and the Simpson-Bowles Moment of Truth project, as well as President Obama in his FY 2014 budget proposal, generally have endorsed ASTRO's recommended policy change to close the self-referral loophole. ASTRO agrees and urges Congress to act this year.

"All evidence confirms that the self-referral loophole must be closed to protect every patient and to preserve the Medicare program," said Dr. Steinberg. "This loophole endangers patients and erodes their trust in us as physicians. In addition, self-referral abuse wastes our nation's already stretched financial resources."

###

ASTRO is a partner in the Alliance for Integrity in Medicare (AIM), a broad coalition of medical societies committed to ending the practice of inappropriate physician self-referral and focused on improving patient care and preserving valuable Medicare resources. In addition to ASTRO, AIM partners include the American Clinical Laboratory Association, the American College of Radiology, the American Physical Therapy Association, the American Society for Clinical Pathology, the Association for Quality Imaging, the College of American Pathologists and the Radiology Business Management Association.

ABOUT ASTRO

ASTRO is the premier radiation oncology society in the world, with more than 10,000 members who are physicians, nurses, biologist, physicists, radiation therapists, dosimetrists and other health care professionals that specialize in treating patients with radiation therapies. As the leading organization in radiation oncology, the Society is dedicated to improving patient care through professional education and training, support for clinical practice and health policy standards, advancement of science and research, and advocacy. ASTRO publishes two medical journals, International Journal of Radiation Oncology Biology Physics (http://www.redjournal.org) and Practical Radiation Oncology (http://www.practicalradonc.org); developed and maintains an extensive patient website, http://www.rtanswers.org; and created the Radiation Oncology Institute (http://www.roinstitute.org), a non-profit foundation to support research and education efforts around the world that enhance and confirm the critical role of radiation therapy in improving cancer treatment. To learn more about ASTRO, visit http://www.astro.org.

---

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 27-Jun-2013
[ | E-mail | Share ]

Contact: Michelle Kirkwood
press@astro.org
703-286-1600
American Society for Radiation Oncology

JAMA study reveals 12 to 21 percent increase in advanced radiation treatment for low-risk prostate cancer patients

Fairfax, Va., June 27, 2013 A new study, "Use of Advanced Treatment Technologies Among Men at Low Risk of Dying from Prostate Cancer," published Tuesday, June 25, 2013, in the Journal of the American Medical Association (JAMA), by Bruce L. Jacobs, MD, MPH, et. al., analyzes treatment data for 55,947 prostate cancer patients (aged 66 years or older) in the Surveillance, Epidemiology and End Results (SEER)-Medicare database from 2004 to 2009. The study found that the use of advanced treatment technologies increased from 32 percent to 44 percent among men with low-risk prostate cancer, from 36 percent to 57 percent among men with high risk of non-cancer mortality, and from 13 percent to 24 percent among men unlikely to die from prostate cancer. In discussion, Dr. Jacobs, et. al., raise several concerns about increased treatment: "aggressive direct-to-consumer marketing and incentives associated with fee-for-service payment may promote the use of advanced treatment technologies;" "more diligence is needed to reduce the potentially unnecessary treatment of men with a low risk of dying from prostate cancer;" and "more immediately, policy change may help curtail the excessive use of advanced treatment technologies among patients least likely to benefit."

Michael L. Steinberg, MD, FASTRO, chairman of the American Society for Radiation Oncology's (ASTRO) Board of Directors, states that Dr. Jacobs, et.al.'s study reaffirms the Society's commitment to closing the self-referral loophole for radiation therapy within the Ethics in Patient Referrals Act, also known as the self-referral law.

ASTRO supports the use of intensity modulated radiation therapy (IMRT) as an appropriate, effective treatment for prostate cancer patients, however, IMRT should be carefully considered along with other effective treatments and management options, including active surveillance, by patients and their doctors. Treatment decisions should not be based on the physician's potential for profit, yet we believe profit-motivated IMRT overuse is rampant due to the proliferation of urology ownership of radiation therapy centers. The abuse of this expensive technology is allowed by a loophole in the federal physician self-referral law. We agree with Dr. Jacobs et. al.'s concerns that financial incentives may be negatively impacting treatment decisions, which we believe are compounded by ownership arrangements protected under the self-referral loophole.

ASTRO expects several independent studies will be published soon demonstrating that self-referral abuse in prostate cancer treatment, particularly among older men, is leading to unnecessary treatment, higher spending and inappropriate patient care. These new reports will add to the already significant body of evidence condemning self-referral abuse. In September 2012, a New England Journal of Medicine article authored by leading health policy experts called for closing the self-referral loophole for radiation therapy and other so-called "ancillary services." In the same month, the GAO issued a scathing report on self-referral in advanced diagnostic imaging titled "Higher Use of Advance Imaging Services by Providers Who Self-Refer Costing Medicare Millions" (GAO-12-966). On November 6, 2012, Bloomberg News published an investigative report indicting self-referral by demonstrating the real-world impact on patients' lives, which received in-depth follow-up by the local newspaper, the Monterey County Herald.

Cumulatively, all of these studies demonstrate that self-referral abuse drives overutilization of expensive technologies. Recently, several bipartisan groups, including the Bipartisan Policy Center and the Simpson-Bowles Moment of Truth project, as well as President Obama in his FY 2014 budget proposal, generally have endorsed ASTRO's recommended policy change to close the self-referral loophole. ASTRO agrees and urges Congress to act this year.

"All evidence confirms that the self-referral loophole must be closed to protect every patient and to preserve the Medicare program," said Dr. Steinberg. "This loophole endangers patients and erodes their trust in us as physicians. In addition, self-referral abuse wastes our nation's already stretched financial resources."

###

ASTRO is a partner in the Alliance for Integrity in Medicare (AIM), a broad coalition of medical societies committed to ending the practice of inappropriate physician self-referral and focused on improving patient care and preserving valuable Medicare resources. In addition to ASTRO, AIM partners include the American Clinical Laboratory Association, the American College of Radiology, the American Physical Therapy Association, the American Society for Clinical Pathology, the Association for Quality Imaging, the College of American Pathologists and the Radiology Business Management Association.

ABOUT ASTRO

ASTRO is the premier radiation oncology society in the world, with more than 10,000 members who are physicians, nurses, biologist, physicists, radiation therapists, dosimetrists and other health care professionals that specialize in treating patients with radiation therapies. As the leading organization in radiation oncology, the Society is dedicated to improving patient care through professional education and training, support for clinical practice and health policy standards, advancement of science and research, and advocacy. ASTRO publishes two medical journals, International Journal of Radiation Oncology Biology Physics (http://www.redjournal.org) and Practical Radiation Oncology (http://www.practicalradonc.org); developed and maintains an extensive patient website, http://www.rtanswers.org; and created the Radiation Oncology Institute (http://www.roinstitute.org), a non-profit foundation to support research and education efforts around the world that enhance and confirm the critical role of radiation therapy in improving cancer treatment. To learn more about ASTRO, visit http://www.astro.org.

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2013-06/asfr-acm062713.php

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Bryan Bickell, Dave Bolland Goals Come In 17-Second Span To Seal Stanley Cup Win For Blackhawks

Michal Rozsival

Chicago Blackhawks defenseman Michal Rozsival, of the Czech Republic, hoists the Stanley Cup after the Blackhawks beat the Boston Bruins 3-2 in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

The Chicago Blackhawks celebrate after beating the Boston Bruins 3-2 in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013, in Boston. (AP Photo/Harry How, Pool)

Chicago Blackhawks

Chicago Blackhawks fans celebrate on Madison St. in Chicago after the Chicago Blackhawks defeated the Boston Bruins 3-2 to win the Stanley Cup on Monday, June 24, 2013. (AP Photo/Paul Beaty)

Andrew Shaw

Chicago Blackhawks center Andrew Shaw skates from the glass after celebrating with fans after the Blackhawks beat the Boston Bruins 3-2 in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013, in Boston. (AP Photo/Elise Amendola)

Rich Peverley, Patrice Bergeron

Boston Bruins centers Rich Peverley, left, Patrice Bergeron (37) and teammates acknowledge their fans after the Chicago Blackhawks beat the Bruins 3-2 in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013, in Boston. (AP Photo/Elise Amendola)

Corey Crawford, Tuukka Rask

Chicago Blackhawks goalie Corey Crawford (50) is congratulated by Boston Bruins goalie Tuukka Rask (40), of Finland, after the Blackhawks beat the Boston Bruins 3-2 in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013, in Boston. (AP Photo/Elise Amendola)

Michal Handzus , Patrice Bergeron

Chicago Blackhawks center Michal Handzus (26), of Slovakia, shakes hands with Boston Bruins center Patrice Bergeron (37) after the Blackhawks beat the Bruins 3-2 in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013, in Boston. (AP Photo/Elise Amendola)

Michal Handzus , Zdeno Chara

Chicago Blackhawks center Michal Handzus (26), and Boston Bruins defenseman Zdeno Chara (33), both of Slovakia, speak at center ice after the Blackhawks beat the Bruins 3-2 in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013, in Boston. (AP Photo/Elise Amendola)

Corey Crawford, Johnny Oduya

Chicago Blackhawks defenseman Johnny Oduya (27), of Sweden, hugs Chicago Blackhawks goalie Corey Crawford (50) after winning Game 6 of the NHL hockey Stanley Cup Finals 3-2 against the Boston Bruins, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

The Chicago Blackhawks pose with the Stanley Cup after beating the Boston Bruins 3-2 in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Chicago Blackhawks left wing Bryan Bickell, center, celebrates his goal with Chicago Blackhawks center Jonathan Toews (19) and Chicago Blackhawks center Michal Handzus (26), of Slovakia, during the third period in Game 6 of the NHL hockey Stanley Cup Finals against the Boston Bruins, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Marcus Kruger, Dave Bolland

Chicago Blackhawks center Dave Bolland (36) celebrates his game-winning goal against the Boston Bruins with Chicago Blackhawks center Marcus Kruger (16) during the third period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. The Blackhawks won 3-2. (AP Photo/Charles Krupa)

Milan Lucic, Duncan Keith, Corey Crawford

Boston Bruins left wing Milan Lucic, left, reacts after scoring past Chicago Blackhawks defenseman Duncan Keith (2) and goalie Corey Crawford, hidden during the third period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Milan Lucic, Duncan Keith, Corey Crawford

Boston Bruins left wing Milan Lucic, foreground, reacts after scoring past Chicago Blackhawks defenseman Duncan Keith (2) and goalie Corey Crawford, right, during the third period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Milan Lucic, Kaspars Daugavins

Boston Bruins left wing Milan Lucic, right, celebrates with left wing Kaspars Daugavins, of Latvia, after scoring against the Chicago Blackhawks during the third period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Johnny Boychuk, Patrick Sharp

Chicago Blackhawks center Patrick Sharp (10) shoots as Boston Bruins defenseman Johnny Boychuk (55) defends during the third period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013 in Boston. (AP Photo/Elise Amendola)

Corey Crawford, Daniel Paille

Boston Bruins left wing Daniel Paille (20) moves the puck in front of Chicago Blackhawks goalie Corey Crawford (50) during the third period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Brandon Saad, Patrice Bergeron, Dennis Seidenberg

Boston Bruins defenseman Dennis Seidenberg (44), of Germany, and center Patrice Bergeron (37) check Chicago Blackhawks left wing Brandon Saad, center, in front of the goal during the second period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013, in Boston. (AP Photo/Harry How, Pool)

David Krejci, Michal Rozsival

Chicago Blackhawks defenseman Michal Rozsival (32), of the Czech Republic, and Boston Bruins center David Krejci (46), of the Czech Republic, tangle during the third period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Johnny Boychuk, Michael Frolik

Chicago Blackhawks center Michael Frolik, top, of the Czech Republic, rides down Boston Bruins defenseman Johnny Boychuk (55) during the third period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013 in Boston. (AP Photo/Elise Amendola)

Patrick Kane, Zdeno Chara, Tuukka Rask

Boston Bruins defenseman Zdeno Chara (33), of Slovakia, turns the puck from the net in front of Boston Bruins goalie Tuukka Rask, right, of Finland, as Chicago Blackhawks right wing Patrick Kane, left, moves in during the second period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013, in Boston. (AP Photo/Harry How, Pool)

Jonathan Toews, Patrick Kane, Tuukka Rask, Dennis Seidenberg

Chicago Blackhawks center Jonathan Toews, left, skates past the net after his puck landed in the net, right, behind Boston Bruins goalie Tuukka Rask, of Finland, as Blackhawks right wing Patrick Kane, right celebrates during the second period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013, in Boston. Watching at center is Boston Bruins defenseman Dennis Seidenberg, of Germany. (AP Photo/Harry How, Pool)

Corey Crawford, Johnny Oduya, Daniel Paille

Chicago Blackhawks defenseman Johnny Oduya, right, of Sweden, knocks Boston Bruins left wing Daniel Paille (20) into the crease in front of Blackhawks goalie Corey Crawford (50) during the first period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013, in Boston. (AP Photo/Harry How, Pool)

Daniel Paille, Chris Kelly, Claude Julien

Boston Bruins center Chris Kelly (23) and left wing Daniel Paille, right, hop from the bench in front of head coach Claude Julien during the second period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Patrick Kane, Michal Rozsival, Duncan Keith

Chicago Blackhawks defenseman Michal Rozsival (32), of the Czech Republic, looks to the scoreboard during the second period in Game 6 of the NHL hockey Stanley Cup Finals against the Boston Bruins, Monday, June 24, 2013 in Boston. (AP Photo/Elise Amendola)

Rich Peverley, Marcus Kruger

Boston Bruins center Rich Peverley (49) checks Chicago Blackhawks center Marcus Kruger (16) during the second period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013 in Boston. (AP Photo/Elise Amendola)

Corey Crawford, Duncan Keith, David Krejci

Boston Bruins center David Krejci (46), of the Czech Republic, and Chicago Blackhawks defenseman Duncan Keith (2) rush the net in front of Blackhawks goalie Corey Crawford (50) during the first period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013, in Boston. (AP Photo/Harry How, Pool)

Joel Quenneville

Chicago Blackhawks head coach Joel Quenneville walks behind the bench during the second period in Game 6 of the NHL hockey Stanley Cup Finals against the Boston Bruins, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Brad Marchand, Corey Crawford

A puck goes past the shoulder of Chicago Blackhawks goalie Corey Crawford (50) during the second period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Patrick Kane, Zdeno Chara, Tuukka Rask, Rich Peverley

Boston Bruins center Rich Peverley (49), defenseman Zdeno Chara, second from left, of Slovakia, and goalie Tuukka Rask, center, of Finland, defend the net against Chicago Blackhawks right wing Patrick Kane (88) during the second period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Brad Marchand, Corey Crawford

Chicago Blackhawks goalie Corey Crawford (50) pokes the puck away from Boston Bruins left wing Brad Marchand (63) during the second period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Johnny Oduya, Daniel Paille

Boston Bruins left wing Daniel Paille (20) checks Chicago Blackhawks defenseman Johnny Oduya (27), of Sweden, during the second period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013 in Boston. (AP Photo/Elise Amendola)

Johnny Oduya, Daniel Paille

Boston Bruins left wing Daniel Paille (20) checks Chicago Blackhawks defenseman Johnny Oduya (27), of Sweden, during the second period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013 in Boston. (AP Photo/Elise Amendola)

Jonathan Toews, Patrick Kane

Chicago Blackhawks center Jonathan Toews (19) celebrates his goal with right wing Patrick Kane (88) during the second period in Game 6 of the NHL hockey Stanley Cup Finals against the Boston Bruins, Monday, June 24, 2013, in Boston. (AP Photo/Elise Amendola)

Carl Soderberg, Johnny Oduya

Boston Bruins center Carl Soderberg (34), of Sweden, and Chicago Blackhawks defenseman Johnny Oduya (27), of Sweden, fight for position along the boards during the second period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013 in Boston. (AP Photo/Elise Amendola)

Tuukka Rask

Boston Bruins goalie Tuukka Rask, of Finland, checks the scoreboard after giving up a goal by Chicago Blackhawks center Jonathan Toews during the second period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Corey Crawford, Johnny Oduya, Daniel Paille

Boston Bruins left wing Daniel Paille (20) ties up Chicago Blackhawks defenseman Johnny Oduya (27), of Sweden, in front of Blackhawks goalie Corey Crawford (50) during the second period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Tuukka Rask, Jonathan Toews

A goal by Chicago Blackhawks center Jonathan Toews hits the net behind Boston Bruins goalie Tuukka Rask (40), of Finland, during the second period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Jonathan Toews, Patrick Kane

Chicago Blackhawks center Jonathan Toews (19) celebrates his goal with right wing Patrick Kane (88) during the second period in Game 6 of the NHL hockey Stanley Cup Finals against the Boston Bruins, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Jonathan Toews, Patrick Kane, Michal Rozsival

Chicago Blackhawks center Jonathan Toews, left, celebrates his goal against the Boston Bruins with right wing Patrick Kane, center, and defenseman Michal Rozsival (32), of the Czech Republic, during the second period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Johnny Oduya, Chris Kelly, Tyler Seguin

Chicago Blackhawks defenseman Johnny Oduya (27), of Sweden, Boston Bruins centers Chris Kelly (23), and Tyler Seguin (19) fight for position in front of Blackhawks goalie Corey Crawford (50) during the first period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013, in Boston. (AP Photo/Harry How, Pool)

Chris Kelly, Corey Crawford

Boston Bruins center Chris Kelly, left, scores past Chicago Blackhawks goalie Corey Crawford (50) during the first period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013, in Boston. (AP Photo/Harry How, Pool)

Corey Crawford, Chris Kelly

Boston Bruins center Chris Kelly (23) scores past Chicago Blackhawks goalie Corey Crawford (50)during the first period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Johnny Boychuk, Duncan Keith

Chicago Blackhawks defenseman Duncan Keith (2) checks Boston Bruins defenseman Johnny Boychuk (55) during the first period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013 in Boston. (AP Photo/Elise Amendola)

Jonathan Toews, Corey Crawford, Niklas Hjalmarsson, Chris Kelly

Chicago Blackhawks defenseman Niklas Hjalmarsson (4), of Sweden, and Boston Bruins center Chris Kelly (23) go down between Chicago Blackhawks goalie Corey Crawford, left, and Chicago Blackhawks center Jonathan Toews, right, during the first period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013 in Boston. (AP Photo/Elise Amendola)

Tuukka Rask, Michal Handzus , Patrice Bergeron

Boston Bruins center Patrice Bergeron (37) and Chicago Blackhawks center Michal Handzus (26), of Slovakia, fight for the puck in front of Boston Bruins goalie Tuukka Rask (40), of Finland, during the first period in Game 6 of the NHL hockey Stanley Cup Finals Monday, June 24, 2013 in Boston. (AP Photo/Elise Amendola)

Standing on artificial legs, Boston Marathon bombing victim Jeff Bauman and Carlos Arredondo, wearing the hat, who assisted him at the scene, waves the Boston Strong banner before Game 6 of the NHL hockey Stanley Cup Finals between the Boston Bruins and the Chicago Blackhawks, Monday, June 24, 2013, in Boston. (AP Photo/Dave Sandford, Pool)

Standing on artificial legs, Boston Marathon bombing victim Jeff Bauman and Carlos Arredondo, wearing the hat, who assisted him at the scene, waves the Boston Strong banner before Game 6 of the NHL hockey Stanley Cup Finals between the Boston Bruins and the Chicago Blackhawks, Monday, June 24, 2013, in Boston. (AP Photo/Dave Sandford, Pool)

Johnny Oduya, Shawn Thornton

Boston Bruins right wing Shawn Thornton (22) and Chicago Blackhawks defenseman Johnny Oduya (27), of Sweden, scrap for the puck during the first period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Chris Kelly

Boston Bruins center Chris Kelly (23) celebrates his goal against the Chicago Blackhawks during the first period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Elise Amendola)

Andrew Shaw

Chicago Blackhawks center Andrew Shaw lays on the ice after taking a puck to the face against the Boston Bruins during the first period in Game 6 of the NHL hockey Stanley Cup Finals, Monday, June 24, 2013, in Boston. (AP Photo/Charles Krupa)

Source: http://www.huffingtonpost.com/2013/06/25/bryan-bickell-dave-bolland-goals-blackhawks_n_3494267.html

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Reading DNA, backward and forward: Biologists reveal how cells control the direction in which the genome is read

June 24, 2013 ? MIT biologists have discovered a mechanism that allows cells to read their own DNA in the correct direction and prevents them from copying most of the so-called "junk DNA" that makes up long stretches of our genome.

Only about 15 percent of the human genome consists of protein-coding genes, but in recent years scientists have found that a surprising amount of the junk, or intergenic DNA, does get copied into RNA -- the molecule that carries DNA's messages to the rest of the cell.

Scientists have been trying to figure out just what this RNA might be doing, if anything. In 2008, MIT researchers led by Institute Professor Phillip Sharp discovered that much of this RNA is generated through a process called divergent expression, through which cells read their DNA in both directions moving away from a given starting point.

In a new paper appearing in Nature on June 23, Sharp and colleagues describe how cells initiate but then halt the copying of RNA in the upstream, or non-protein-coding direction, while allowing it to continue in the direction in which genes are correctly read. The finding helps to explain the existence of many recently discovered types of short strands of RNA whose function is unknown.

"This is part of an RNA revolution where we're seeing different RNAs and new RNAs that we hadn't suspected were present in cells, and trying to understand what role they have in the health of the cell or the viability of the cell," says Sharp, who is a member of MIT's Koch Institute for Integrative Cancer Research. "It gives us a whole new appreciation of the balance of the fundamental processes that allow cells to function."

Graduate students Albert Almada and Xuebing Wu are the lead authors of the paper. Christopher Burge, a professor of biology and biological engineering, and undergraduate Andrea Kriz are also authors.

Choosing direction

DNA, which is housed within the nucleus of cells, controls cellular activity by coding for the production of RNAs and proteins. To exert this control, the genetic information encoded by DNA must first be copied, or transcribed, into messenger RNA (mRNA).

When the DNA double helix unwinds to reveal its genetic messages, RNA transcription can proceed in either direction. To initiate this copying, an enzyme called RNA polymerase latches on to the DNA at a spot known as the promoter. The RNA polymerase then moves along the strand, building the mRNA chain as it goes.

When the RNA polymerase reaches a stop signal at the end of a gene, it halts transcription and adds to the mRNA a sequence of bases known as a poly-A tail, which consists of a long string of the genetic base adenine. This process, known as polyadenylation, helps to prepare the mRNA molecule to be exported from the cell's nucleus.

By sequencing the mRNA transcripts of mouse embryonic stem cells, the researchers discovered that polyadenylation also plays a major role in halting the transcription of upstream, noncoding DNA sequences. They found that these regions have a high density of signal sequences for polyadenylation, which prompts enzymes to chop up the RNA before it gets very long. Stretches of DNA that code for genes have a low density of these signal sequences.

The researchers also found another factor that influences whether transcription is allowed to continue. It has been recently shown that when a cellular factor known as U1 snRNP binds to RNA, polyadenylation is suppressed. The new MIT study found that genes have a higher concentration of binding sites for U1 snRNP than noncoding sequences, allowing gene transcription to continue uninterrupted.

A widespread phenomenon

The function of all of this upstream noncoding RNA is still a subject of much investigation. "That transcriptional process could produce an RNA that has some function, or it could be a product of the nature of the biochemical reaction. This will be debated for a long time," Sharp says.

His lab is now exploring the relationship between this transcription process and the observation of large numbers of so-called long noncoding RNAs (lncRNAs). He plans to investigate the mechanisms that control the synthesis of such RNAs and try to determine their functions.

"Once you see some data like this, it raises many more questions to be investigated, which I'm hoping will lead us to deeper insights into how our cells carry out their normal functions and how they change in malignancy," Sharp says.

The research was funded by the National Institutes of Health, the National Cancer Institute and the National Institute of General Medical Sciences.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/vK48xKSPdxQ/130624141412.htm

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Does This Self-Burying Bot Mean We're Close to Robo-Tremors?

We already have autonomous robots that can drive, fly, swim?even operate in space. And now, thanks to researchers at the Carnegie Mellon University Robotics Institute, we'll soon be dealing with bots that can tackle the final frontier here on earth?or should we say inside earth?with a self-burrowing robot that works underground.

Read more...

Source: http://feeds.gawker.com/~r/gizmodo/full/~3/0KiCZFH7RjM/does-this-self-burying-bot-mean-were-close-to-robo-tre-571597221

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Skywire Pictures Nik Wallenda Crosses Grand Canyon - Business ...

UPDATE: He made it! After nearly 23 minutes, Nik Wallenda is the first human to ever cross the Little Colorado River Gorge on a wire.

Daredevil Nik Wallenda has a wife, three children, and he's been training for one moment his entire life:

To tightrope walk across the Grand Canyon without any safety net or harness. Making it across means life, falling means death.

The National Park Service would never allow a stunt like this over the Grand Canyon ? so Wallenda had to settle for the "little Grand Canyon" over the gorge of the Colorado River near Cameron, Arizona, on tribal lands of the Navajo Nation.

Wallenda's grandfather died before viewers' eyes on live television trying to do a similar, harness-free walk.

"Thank you Jesus," Wallenda kept repeating with each step. "You're my king, you're my protector, you're my shield, you're my strength, you're my lord." He battled high winds and balanced with a 45 pound bar on the 2-inch wire. He reached the half-way point on the wire at the 11:30 minute mark.

The quarter-mile walk at 1,500 feet in the air took more than 20 minutes ? in winds ranging from a safe 18 mph to a more treacherous 30 mph. Wallenda knelt twice to wait out the stronger wind.

Here's his bio on Discovery's website:

Nik Wallenda is known as 'The King of the High Wire.' He is the seventh generation of the legendary Great Wallendas and began walking the wire at age 4. He and his family have performed some of the most famous stunts in the world, but no one else has ever dared to take on the Grand Canyon.

His incredible walk was aired on the Discovery Channel Sunday evening on a live feed.

This isn't the first feat on the tightrope for Wallenda. Last year, he successfully?walked across Niagara Falls, according to NPR.

Here are some shots of him crossing the canyon.

Discovery Channel

Source: http://www.businessinsider.com/a-man-is-about-to-tight-rope-walk-across-the-grand-canyon-without-any-wires-2013-6

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2014 Buick LaCrosse Test Drive

On-Sale Date: Third-quarter 2013

Price: $34,060 to $46,875

Competitors: Acura TL, Lincoln MKZ, Lexus ES, Chrysler 300, Toyota Avalon, Nissan Maxima

Powertrains: 2.4-liter I-4 with e-Assist, 182 hp, 172 lb-ft; 3.6-liter V-6, 304 hp, 264 lb-ft; six-speed automatic transmission; FWD or AWD

EPA Fuel Economy (city/hwy): 25/36 (I-4), 17?18/28 (V-6)

What's New: Buick's full-size sedan noses into the marque's 110th anniversary behind a prettier face with articulating headlights, a grille styling more in line with its smaller siblings the Regal and Verano, LEDs on both ends, and active aero shutters in front to eke out a bit more fuel economy. Bigger improvements are found inside the cabin, where upgraded materials, introduction of a second-generation IntelliLink system, and several new safety-oriented features all make life better for occupants.

Revised suspension tuning includes real-time adjustable damping, and the HiPer front-strut design now comes standard in the top two trim levels (previously you had to pony up for a separate Touring package to get it). This is a midlife freshening for the LaCrosse Buick introduced for the 2010 model year, so there are no major changes to the extended GM Epsilon II architecture it shares with the Cadillac XTS and Chevrolet Impala.

Tech Tidbit: A rear-view camera is standard on all but the base model, while Buick offers a pair of safety packages with up to nine sensors to keep the driver alert. Driver Confidence I ($2125) includes forward-collision alert, lane-departure warning, lane-change alert, side blind-zone alert, rear cross-traffic alert, HID articulating headlamps, fog lamps and a head-up display. For another $1745 you can add Driver Confidence II and get the haptic seat (it vibrates to alert the driver rather than adding another annoying beep to your life), adaptive cruise control, and collision preparation, which includes "mitigation" braking if the driver doesn't hit the pedal soon enough.

Driving Character: Buick long ago shed the bloat and float approach to ride and handling, but we still were pleasantly surprised by how nimbly this big, comfort-oriented car dealt with the challenge of twisting roads snaking around lakes in southern Michigan. An Acura TL would have been more engaging, but a Lincoln MKZ less so. We drove only V-6 models, in front- and all-wheel-drive configurations, and found the suspension in the upper two trim levels superior in both ride comfort and handling. You can't get the adaptive damping with AWD, though.

Favorite Detail: We'll cheat and name two. First, the head-up display keeps your eyes on the road. Second, the fact that the haptic seat that vibrates warnings about lane-departure, something in your blind spot, rear cross-traffic, or obstacles behind the car minimizes distractions and avoids alarming passengers.

Driver's Grievance: The AWD model lacks the best suspension bits and the smooth ride of its counterpart. And it just feels heavy. We'd recommend it only for those in regions with the worst winter weather, and even then we'd advise shopping AWD alternatives.

Bottom Line: The full-size sedan segment has been fading as buyers gravitate to crossovers or smaller cars. Buick has seen slow but steady erosion in U.S. LaCrosse sales (a minor concern, since sales in Asia are more than double those in North America), in part because shoppers can find the Enclave, Regal, Verano and Encore in the same showrooms. This well-executed refresh comes just in time to meet increasing competition. The exterior tweaks are all improvements, while the interior upgrades are sharp and rich-looking, with only a little too much gloss remaining on the dark-colored version of the soft-touch lower dashboard (in lighter colors, it looks good).

Spare a moment to applaud Buick's latest IntelliLink infotainment system, which does several things other systems could emulate. It cuts the center-stack-button count from 17 to seven, but still includes two knobs for volume and tuning, and uses labels big enough to be read at a glance without peering. As these things go, it's intuitive and useful. Expect to see it on the revised Regal, coming soon.

By year-end the oldest Buick in dealerships will be the Verano, introduced for 2012. Talk about keeping things fresh.

Source: http://www.popularmechanics.com/cars/reviews/drives/2014-buick-lacrosse-test-drive-15623758?src=rss

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